Université d'Auvergne

IDENTITE THEMATIQUES

Composition

Enseignants-Chercheurs 10 (4,6 ETP)
Chercheurs 1 dont HDR 6
PH ou Prof associés 3 (1,2 ETP)
IATOSS 5 (4,5 ETP)
Post-Doctorants 1
Doctorants 5

PRODUCTION SCIENTIFIQUE

DARFEUILLE-MICHAUD A, BOUDEAU J, BULOIS P, NEUT C, GLASSER AL, SWIDSINSKI A, BEAUGERIE L, BARNICH N, BRINGER MA, COLOMBEL JF. High prevalence of invasive Escherichia coli strains in patients with Crohn's
disease. Gastroenterology 2004; 127:412-421.

CHEN Y, DELMAS J, SIROT J, SHOICHET B, BONNET R. Atomic resolution structures of CTX-M beta-lactamases: extended spectrum activities from increased mobility and decreased stability. J Mol Biol 2005; 348:349-362.

CHEN Y, SHOICHET B, BONNET R. Structure, function, and inhibition along the reaction coordinate of CTX-M beta-lactamases. J Am Chem Soc 2005; 127:5423-5434.

BRINGER MA, GLASSER AL, CHING-HSUAN T, MERESSE S, DARFEUILLE-MICHAUD A. The Crohn's diseaseassociated adherent-invasive Escherichia coli strain LF82 replicates in mature phagolysosomes within J774 macrophages. Cellular Microbiology 2006; 8:471-484.

BARNICH N, CARVALHO F, GLASSER AL, DARCHA C, JANTSCHEFF P, ALLEZ M, BOMMELAER G, DESREUMAUX P, COLOMBEL JF, DARFEUILLE-MICHAUD A. CEACAM6 a receptor of adherent-invasive Escherichia coli supports ileal mucosa colonization in Crohn’s disease patients. Journal of Clinical Investigation 2007;117:1566-1574.

CLARET L, MIQUEL S, VIEILLE N, RYJENKOV DA, GOMELSKY M, DARFEUILLE-MICHAUD A. The flagellar sigma factor FliA regulates adhesion and invasion of Crohn's disease-associated Escherichia coli via a c-di-GMPdependent pathway. Journal of Biological Chemistry 2007;282:33275-33283.

DELMAS J, CHEN Y, PRATI F, ROBIN F, SHOICHET BK, BONNET R. Structure and dynamics of CTX-M enzymes reveal insights into substrate accommodation by extended-spectrum beta-lactamases. Journal of Molecular Biology 2008;375:192-201.